Application of carboxymethyl fluorescein 6-fam modified PNA peptide nucleic acid 6-fam-pna|cy3-pna fluorescent dye Cy3 coupling PNA peptide nucleic acid

Carboxymethyl fluorescein 6-FAM modification PNA Peptide nucleic acid 6-FAM-PNA|CY3-PNA Fluorescent dyes CY3 coupling PNA Application of peptide nucleic acid

Peptide nucleic acid (Peptide Nucleic Acid, PNA) It is a kind of synthetic DNA Analogues , Structurally, it retains DNA Base and deoxyribose , Just the original ribose - The phosphate skeleton is replaced by an amide bond skeleton similar to a peptide bond （ The red circle in the figure indicates ） replace . therefore ,PNA Still follow the principle of complementary base pairing , And the skeleton turns from negative to nearly neutral , Weakened the electrostatic repulsion between double stranded nucleic acids , bring LNA And DNA or RNA The binding stability and specificity of are greatly improved . and ,PNA The amide bond skeleton of is not easy to be hydrolyzed by nuclease and protease , Make it extremely stable in vivo and in vitro .

Peptide nucleic acid pna Custom products ：

Sulfhydryl functionalized peptide nucleic acid PNA
NH2-PNA
COOH-PNA
MAL-PNA
NHS-PNA
N3-PNA
Alkyne-PNA
SH-PNA
Hydrazide-PNA
Biotin-PNA
CHO-PNA
OH-PNA
VA-PNA

PYR-PNA Mark FITC Fluorescent groups
HiLyte Fluor 488 Mark PNAs Peptide nucleic acid
Methoxycoumarin labeled peptide nucleic acid PNA
Dansulfonyl chloride labeled peptide nucleic acid PNA
AMC Labeled peptide nucleic acid PNA
Aminocoumarin labeled peptide nucleic acid PNA
Dabcyl Labeled peptide nucleic acid PNA
CY2 Labeled peptide nucleic acid PNA
FAM Labeled peptide nucleic acid PNA
Alexa fluor488 Labeled peptide nucleic acid PNA
FITC Labeled peptide nucleic acid PNA
Alexa fuor 430 Labeled peptide nucleic acid PNA
5-FAM Labeled peptide nucleic acid PNA
Alexa fhuor 532 Labeled peptide nucleic acid PNA

Qi Yue bio Small make up axc.2020.07.19