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Review questions of Biochemistry VIII. Lipid metabolism
2022-07-22 09:42:00 【Cold mountains are crystal clear】
This section focuses on
Activation of fatty acids , Fatty acid β- oxidation 、 Energy production .
The concept of ketone body 、 Generation and utilization , The physiological significance of ketone body production is related to ketosis .
Anabolism of fatty acids , The difference between fatty acid synthesis and decomposition , Acetyl coenzyme A Transportation and activation of .
Acetyl coenzyme A Regulation of carboxylase , Malonyl coenzyme A( Malonyl coenzyme A ) Regulation of carnitine .
glycerol -3- The role of phosphoric acid in fat synthesis and decomposition .
Raw materials for cholesterol synthesis 、 Site and key enzymes .
1. Briefly describe the total process of fatty acid catabolism .
2. Brief introduction of fatty acids β - Steps and significance of oxidation .
3. Briefly describe the reaction process of fatty acid activation .
4. Fatty acids β- The speed limiting step of oxidation is __________ , The transport carrier of this process is _____ , The enzymes needed are ________________________________ .
5. Briefly describe the fatty acids in mitochondria β- The reaction process of oxidation .
6. List fatty acids β- Products of oxidation .
7. Try to calculate 1 Molecular myristic acid ( Saturated fatty acids , Molecular formula C14H28O2) Produced by complete oxidative decomposition ATP, And write the calculation process .
8. When unsaturated fatty acids are oxidized , The additional steps required are ___________________________________ .
9. When fatty acids with odd carbon atoms are oxidized , The final product is different from the oxidation of fatty acids with even carbon atoms __________ , After a series of reactions, this substance finally becomes __________ , Get into __________ The metabolic process .
10. Briefly describe the definition of ketone body .
11. stay _______________ Under the condition of ,_____ It can be converted into ketones .
12. Briefly describe the utilization of ketone bodies .
13. Briefly describe the physiological significance of ketone metabolism .
14. Briefly describe ketosis 、 The concept of metabolic acidosis .
15. Briefly describe the process of ketone body regulation .
16. Fatty acid synthesis sites are ____________________ , Synthetic raw materials are __________ , The raw material mainly comes from __________ and __________ .
17. Briefly describe the differences between fatty acid synthesis and catabolism .
18. Acetyl coenzyme A Transmembrane transport utilization _______________ , Briefly describe its mechanism .
19. Briefly describe acetyl coenzyme A Activation mechanism of .
20. Briefly describe the reaction steps of fatty acid synthesis .
21. List the regulatory sites of fatty acid synthesis .
22. Brief introduction through acetyl coenzyme A Carboxylase regulates fatty acid synthesis .
23. Briefly describe the effect of glucose metabolism on lipid metabolism in hepatocytes .
24. Briefly describe the metabolic regulation of fatty acid decomposition .
25. Brief description of fat hydrolysis ( Glycerol decomposition ) The process of .
26. Fat synthesis sites are __________________ , Synthetic precursors are ______________ .
27. Take triglycerides as an example , Explain the process of fat anabolism .
28. The site of cholesterol synthesis is ____________________ , And write the equation of synthetic reaction .
29. Briefly describe the process of cholesterol synthesis .
30. Briefly describe the regulation process of cholesterol synthesis .
31. List the substances and parts that cholesterol can transform .
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