5-carboxyl tetramethyl rhodamine labeled peptide nucleic acid PNA | TMR ahx- (Tamra ahx-) -pna | fluorescein labeled peptide nucleic acid mechanism

5- Carboxyl tetramethyl rhodamine labeled peptide nucleic acid PNA|TMR-Ahx-（TAMRA-Ahx-）-PNA| The mechanism of fluorescein labeling peptide nucleic acid

Peptide nucleic acid , Also known as PNA (Peptide Nucleic Acid), yes - A class of novel nucleic acid analogues , Its characteristics are : 1. The ability of writing with nucleic acids is stronger than that of hybridization between nucleic acids ; 2. The thermal stability is higher than that of hybrids between nucleic acids ; 3. The anti enzymatic hydrolysis ability is enhanced , Because of its non peptide and non nucleic acid structural characteristics , Neither protease nor nuclease can degrade peptide nucleic acid (PNA). at present , Peptide nucleic acid (PNA) It is widely used in Chemistry 、 biology 、 Antisense drugs 、 Molecular recognition 、 Genetic diagnosis and other fields . At present, many non classical peptide nucleic acids are also developed , Such as gamma-PN etc. .

About peptide nucleic acid synthesis :

1. Composite content : Conventional synthesis 、 Special peptide nucleic acid synthesis , Such as Telomere FISH , gamma-PNA etc. ;
2. PNA modification : Fluorescent modification 、 Biotin modification 、 Polypeptide modification 、 Glycosylation and DNA Embellishment, etc , If the customer needs to decorate in other aspects , Can be proposed , We will try our best to meet its research needs .
3. Synthetic scale : The conventional synthesis scale is : 50 And 100nmole , Purity is usually >90% , Free collection c. Synthetic scale : The conventional synthesis scale is : 50 And 100nmole , Purity is usually >90% , Free delivery can also be determined according to customer requirements .

Peptide nucleic acid pna Custom products ：

Palmitic acid labeling pna Peptide nucleic acid
Digoxin Labeling pna Peptide nucleic acid
Azide marking pna Peptide nucleic acid
Methylene blue marking pna Peptide nucleic acid
Glycosylation pna Peptide nucleic acid
DNA Modified peptide nucleic acid pna DNA-PNA
Lys Amino acid modification pna Peptide nucleic acid Lys-PNA
DOTA modification pna Peptide nucleic acid DOTA-PNA
NOTA modification pna Peptide nucleic acid NOTA-PNA

Tyr-PNA
Leu-PNA
Val-PNA
Ala-PNA
Arg-PNA
Lys-PNA
Asp-PNA
Ile-PNA
Ser-PNA
Thr-PNA
Glu-PNA
Met-PNA
Phe-PNA

Qi Yue bio Small make up axc.2020.07.19